Fact-checked by Lucent 3 months ago
Total Sources: 49
Verified Claims: 45
Scientific Sources: 18
Isopure Zero Carb Protein Powder is a dietary supplement marketed for its high protein content (25g per scoop) derived from 100% whey protein isolate, with minimal carbohydrates, sugar, and fat. It aims to support muscle building, recovery, weight management, and overall protein intake [27].
Hal and Ernie started a company intending to change the nutrition industry [26].
Isopure was introduced, revolutionizing protein drinks [26].
Whey protein isolate and dairy product solids were recognized as GRAS (Generally Recognized as Safe) by the FDA [18].
A class-action lawsuit was filed against Nature’s Best and GNC for allegedly misrepresenting the amount of whey protein in Isopure Zero-Carb and Low-Carb Protein Powders [30].
Whey protein can assist in reducing LDL-cholesterol in individuals under 50 years old and when combined with exercise [5].
Whey protein intake can improve triglyceride and HDL-c levels [6].
Excessive whey protein consumption may lead to kidney and liver issues, acne, aggression, and changes in gut microbiota [15].
Some protein powders, including whey protein, may contain heavy metals [19], [20], [24], [25].
The effects of whey protein supplementation on indices of cardiometabolic health: A systematic review and meta-analysis of randomized controlled trials
Whey protein supplementation had no effect on HDL-cholesterol concentration but did elicit a reduction in LDL-cholesterol in individuals aged <50 years and when combined with exercise [5].
Impact of whey protein on lipid profiles: A systematic review and meta-analysis
Whey protein intake can improve TG and HDL-c significantly without significant effects on TC and LDL-c levels [6].
Whey protein supplementation and its potentially adverse effects on health: a systematic review
Chronic and excessive use of whey protein may cause adverse effects, especially on kidney and liver function [15].
Protein Isolate Supplements and Urinary Stone Risk
Urine calcium was significantly lower and pH was higher with pea and soy protein compared to whey protein consumption. Urine oxalate was significantly higher in pea phase compared to whey [13].
Whey Protein Dietary Supplements: Metal Exposure Assessment and Risk Characterization
A high daily consumption scenario (100 g PS/day) and when the maximum concentrations are considered, Cr, Zn, Fe, Mo, and Mg dietary intakes of these metals exceed the daily recommended intakes and could pose a risk [16].
Generally regarded as safe for most individuals when consumed in moderation. However, potential risks include heavy metal contamination, digestive issues, and kidney strain from excessive protein intake [15], [16], [22].
The presence of heavy metals in protein powders is a recognized issue, stemming from environmental contamination and absorption by plants [20], [24], [25]. Consumers should be aware of the source and quality of protein supplements and consider products that undergo third-party testing to ensure purity [34], [35].
Other protein sources
To ensure a balanced intake of nutrients and minimize potential risks associated with excessive whey protein consumption, consider diversifying protein sources with whole foods [21].
Where to find: Lean meats, fish, eggs, dairy, legumes, nuts, and seeds [Source 21].
Plant-based protein powders
For individuals with lactose intolerance or dairy allergies, plant-based protein powders such as soy, pea, or rice protein offer a suitable alternative [13].
Where to find: Amazon, Walmart, health food stores [Source 23].
Other Whey Protein Products
If still wanting to use whey protein, consider other brands that have been third-party tested [34], [35].
Consume protein powder in moderation as part of a balanced diet [49].
Choose protein powders with minimal added sugars and artificial ingredients [37].
Prioritize whole food sources of protein whenever possible [21].
Consult with a healthcare professional or registered dietitian before starting a protein supplement regimen [20], [22].