High-Fructose Corn Syrup 55
Summary
What it is
Common uses
Public Perception
Anxiety level
Cultural claims
Source sentiment
History
Timeline
Origin
Science
Key findings
Studies
Safety status
Nuance
Alternatives
Swaps
Avoidance tips
References

Fact-checked by Lucent 3 months ago

High-Fructose Corn Syrup 55

ingredientAdded Sugars

Total Sources: 43

Verified Claims: 29

Scientific Sources: 22

Also known as: HFCS-55

Summary

High-fructose corn syrup 55 (HFCS 55) is a sweetener derived from corn starch, commonly used in the food and beverage industry due to its cost-effectiveness and desirable properties [16], [28]. It consists of approximately 55% fructose and 45% glucose [16], [29].

What it is

HFCS 55 is a liquid sweetener produced by enzymatically converting glucose in corn syrup to fructose [16], [28], [29]. This results in a mixture that is sweeter than regular corn syrup and comparable to sucrose [28], [29].

Common uses

  • Soft drinks [16], [28], [29]

  • Processed foods [16]

  • Cereals [16]

  • Baked goods [16]

Public Perception

Anxiety level

Moderate. While scientific consensus suggests HFCS is not significantly different from other sweeteners like sucrose, public perception and some studies create a level of anxiety regarding its consumption [5], [16], [23].

Cultural claims

  • HFCS is believed by some to be a major contributor to childhood obesity and other chronic diseases [23].

  • Some believe HFCS is not as safe as other sweeteners [16].

Source sentiment

The sentiment surrounding HFCS 55 is mixed. Some sources present it as a cost-effective and functionally useful ingredient, while others express concerns about its potential health impacts [24], [28].

History

Timeline

1960

Japanese scientists discover the enzyme that makes large-scale HFCS production possible [23].

1970

HFCS was first marketed in the early 1970s by the Clinton Corn Processing Company [28], [29].

1973

The Farm Bill introduces subsidies for growing certain crops, encouraging a boom in corn production and lowering its price, which made HFCS financially viable [27].

1970

American food manufacturers began to change their recipes for foods like cereal, ice cream, baked goods and soda [23].

2000

Use of HFCS started falling as food companies reacted to shifts in consumer taste and concerns over high-fructose corn syrup’s impact on health [23].

Origin

HFCS was developed as a cheaper alternative to sucrose [28], [30].

First appeared: 1970

Science

Key findings

  • HFCS consumption was associated with a significant increase in CRP levels compared to sucrose [5], [6].

  • Increased hepatic lipid content and decreased insulin sensitivity have critical roles in the development of cardiometabolic diseases [13].

  • The proportion of fructose to glucose in both HFCS 42 and HFCS 55 is similar to that of sucrose [16].

Studies

The effect of high-fructose corn syrup vs. sucrose on anthropometric and metabolic parameters: A systematic review and meta-analysis [5, 6]

HFCS intake does not significantly change weight, waist circumference, body mass index, fat mass, total cholesterol, high-density lipoprotein, low-density lipoprotein, triglyceride, systolic blood pressure, and diastolic blood pressure when compared to sucrose. HFCS consumption was associated with a significant increase in CRP levels compared to sucrose [5], [6].

The Dose-Response Effects of Consuming High Fructose Corn Syrup-Sweetened Beverages on Hepatic Lipid Content and Insulin Sensitivity in Young Adults [13]

Significant linear dose-response effects were observed for increases of hepatic lipid content and glucose and insulin AUCs during OGTT, and for decreases in the Matsuda and Predicted M indices of insulin sensitivity [13].

Safety status

The FDA states that it is not aware of any evidence showing that HFCS is less safe than traditional sweeteners such as sucrose and honey [16], [28], [29].

Nuance

While some studies suggest potential negative impacts of HFCS on certain health markers, the overall scientific consensus is that HFCS and sucrose have similar metabolic effects. More research is needed to fully understand the nuanced differences and long-term health outcomes [5], [16].

Alternatives

Honey

Honey has a lower glycemic index than sugar and may lower blood sugar and improve insulin sensitivity [32].

Stevia

Stevia may help lower blood pressure and improve blood sugar levels [32].

Monk Fruit Extract

Monk fruit extract is a natural sweetener with zero calories and may have antioxidant properties [34].

Avoidance tips

  • Read food labels carefully to identify products containing added sugars, including HFCS [37], [38].

  • Choose whole, unprocessed foods whenever possible to minimize added sugar intake [37].

  • Limit consumption of sugar-sweetened beverages, which are a major source of added sugars [22], [37].

References

1.

https://www.who.int/publications/i/item/9241206837