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Scientific Sources: 26
Artificial trans fats are industrially produced fats created by adding hydrogen to vegetable oils to make them solid at room temperature [12], [22], [35]. They have been used in processed foods to extend shelf life, enhance flavor and texture, and are a cheaper alternative to animal fats [35], [37], [44]. However, they have no known health benefits and increase the risk of heart disease [20], [25], [33].
Procter & Gamble releases Crisco, the first hydrogenated shortening product [37].
FDA releases its final determination that PHOs are no longer Generally Recognized as Safe (GRAS) [16], [17].
Trans fats increase LDL (bad) cholesterol and decrease HDL (good) cholesterol, raising the risk of heart disease and stroke [22], [25], [33], [44].
Consumption of trans fats is associated with increased risk of systemic inflammation, metabolic syndrome, neurodegenerative diseases, and cardiovascular diseases [11], [14].
Dietary trans fatty acids are associated with a higher risk of colorectal cancer [8].
Industrial trans fats specifically exert toxicity by targeting ASK1, and polyunsaturated fatty acids (PUFAs) can suppress this effect [11].
Trans fat intake has been linked to dyslipidemia and perhaps increased body fat [13].
Dietary trans fatty acids and risk of colorectal cancer: a systematic review and meta-analysis of observational studies
Dietary trans fats were associated with a higher risk of colorectal cancer, particularly colon cancer [8].
A comprehensive toxicological analysis of trans-fatty acids (TFAs) reveals a pro-apoptotic action specific to industrial TFAs counteracted by polyunsaturated FAs
Industrial trans fats specifically exert toxicity by targeting ASK1, and that PUFAs serve as their effective suppressor [11].
Effect of trans fatty acid intake on abdominal and liver fat deposition and blood lipids: a randomized trial in overweight postmenopausal women
Dietary TFA on cardiovascular disease risk involves induction of dyslipidemia, and perhaps body fat [13].
Trans fatty acids – Effects on systemic inflammation and endothelial function
TFA are pro-inflammatory and appear to induce endothelial dysfunction [14].
Read food labels carefully to identify and avoid products containing partially hydrogenated oils [26], [34], [44].
Limit consumption of fried foods, commercial baked goods, and processed snacks [22], [44].
Choose products with 0g trans fat and no partially hydrogenated oils in the ingredient list [26], [34], [44].